The US Open revealed Thursday that Daniil Medvedev and Nick Kyrgios will play their first-round matches on Monday, while Rafael Nadal will begin his chase for a fifth title at Flushing Meadows on Tuesday.

The top half of the men’s singles draw will compete on Monday and the bottom half will play on Tuesday.

Along with Medvedev and Kyrgios, other stars taking the court Monday will include fourth seed Stefanos Tsitsipas, fifth seed Casper Ruud, sixth seed Felix Auger-Aliassime, former World No. 1 Andy Murray and 2020 US Open champion Dominic Thiem.

On Tuesday, joining Nadal in action will be third seed Carlos Alcaraz, seventh seed Cameron Norrie, eighth seed Hubert Hurkacz and 2019 Intesa Sanpaolo Next Gen ATP Finals champion Jannik Sinner.

The tournament announced that Monday’s full order of play will be released by 6 p.m. ET on Friday.

View Men’s Singles Draw

There were plenty of intriguing first-round matches when the US Open draw was revealed on Thursday, led by a tantalising clash between close friends Nick Kyrgios and Thanasi Kokkinakis.

ATPTour.com highlights five matches to watch in the opening round at Flushing Meadows.

No. 23 Nick Kyrgios vs. Thanasi Kokkinakis
The ‘Special Ks’ have been one of the most exciting doubles teams on the circuit this season. They started their season off with a bang by winning the Australian Open. At the time, Kokkinakis said: “To be a Grand Slam champion with my boy, we have known each other since we were eight, nine years old, done some serious things together, have had some serious experiences, but this is incredible.”

The Australians often refer to each other as “brothers”, but only one can advance to the second round at Flushing Meadows. Their first-round clash will be their first ATP Head2Head meeting and first match against one another since they competed on the ATP Challenger Tour in 2014.

Kyrgios is one of the world’s most in-form players. The 27-year-old has shown the most consistency of his career to reach the final at Wimbledon, win the Washington title and advance to the quarter-finals in Montreal, where he eliminated World No. 1 Daniil Medvedev. However, nobody on Tour knows him better than Kokkinakis, who thrives on the big stages with an aggressive game of his own.

Kokkinakis’ resume includes a win against Roger Federer, and last year he pushed Stefanos Tsitsipas to five sets at the Australian Open. That makes for a blockbuster showdown between the great friends.

No. 12 Pablo Carreno Busta vs. Dominic Thiem
Dominic Thiem will have to be sharp for his first match at the US Open since lifting his maiden major trophy at Flushing Meadows two years ago. The Austrian will face 12th seed Pablo Carreno Busta, who recently claimed his first ATP Masters 1000 title in Montreal.

Thiem has struggled to find his best form since returning from a wrist injury in March. He does have one thing on his side, though: a 7-0 ATP Head2Head advantage against Carreno Busta. One of those clashes came at the US Open in 2016, when Thiem rallied for a four-set victory.

Form tilts in the Spaniard’s direction after his Canadian breakthrough, and his solid baseline game will force the Austrian to come up with the spectacular winners he has so often hit throughout his career. Will Thiem be able to rely on their past history to earn a first-round upset?

No. 24 Francisco Cerundolo vs. Andy Murray
One year ago, 2012 US Open champion Andy Murray suffered a heartbreaking loss in the first round in New York against Tsitsipas. The Scot will have another chance to oust a seed in the opening round when he plays 24th seed Francisco Cerundolo.

Murray showed signs of good form in Cincinnati, where he emerged victorious from a two-hour, 58-minute epic against Stan Wawrinka and pushed Cameron Norrie hard in the second round before cramping got the best of him.

But his first ATP Head2Head meeting against Cerundolo should prove tricky. Although the 24-year-old has lost three consecutive matches since reaching the Hamburg semi-finals, the rising Argentine has found success on hard courts before. Earlier this year, he made a stunning run to the Miami semi-finals with wins over stars including Gael Monfils and Jannik Sinner.

No. 3 Carlos Alcaraz vs. Sebastian Baez
Last November, Carlos Alcaraz met Sebastian Baez in the semi-finals of the Intesa Sanpaolo Next Gen ATP Finals. Alcaraz was World No. 32 and Baez No. 111. Ten months later, both men have come a long way. Alcaraz is the third seed at the US Open and Baez was the last player who did not receive a seed. 

In their first meeting, Alcaraz prevailed in Milan 4-2, 4-1, 4-2. His powerful game is capable of blasting through all opponents. Baez is plenty aggressive himself, though, and he will try to take it to the Spaniard to play on his own terms.

The Argentine is 1-3 against Top 10 opponents, with his victory coming in the Bastad semi-finals against Andrey Rublev. Will Baez be able to earn another big win against Alcaraz?

No. 14 Diego Schwartzman vs. Jack Sock
There are few fans in the world like those in New York at the US Open. Jack Sock, who thrills crowds throughout the world with his flashy play, will try to use that to his advantage against 14th seed Diego Schwartzman.

The pair’s only meeting came in 2017 on clay at the Internazionali BNL d’Italia, where Sock prevailed in three sets. Since then, both men have spent time in the world’s Top 10 and have proven their ability against the best players on Tour. Sock will try to dominate the action with his forehand and speed around the court, while Schwartzman has almost no weaknesses and will try to attack the American’s backhand.

Schwartzman is a two-time quarter-finalist at the US Open. The favourite will try to avoid an early exit this edition of the year’s final major.

Rafael Nadal and Carlos Alcaraz are on the same half of the US Open draw as the battle for World No. 1 heats up, while top seed and defending champion Daniil Medvedev faces a tricky path at Flushing Meadows, which could include Nick Kyrgios in the fourth round.

Nadal enters the year’s final Grand Slam in pole position in the battle for World No. 1. The four-time US Open champion controls his own destiny as he tries to return to the top spot. If the 36-year-old lifts the trophy, he will climb to the top of men’s tennis’ mountain.

Nadal will begin his pursuit of a fifth title in New York against Australian Rinky Hijikata, who tested Medvedev in a tight two-setter earlier this month in Los Cabos. If Nadal advances, the lefty could in the second round play Fabio Fognini, who upset him here in five sets in 2015.

Other notable players in Nadal’s quarter of the draw are seventh seed Cameron Norrie, 14th seed Diego Schwartzman, 19th seed Denis Shapovalov and home favourite Frances Tiafoe, the 22nd seed.

Alcaraz has a chance to become the youngest No. 1 in the history of the Pepperstone ATP Rankings over the coming fortnight. The 2021 US Open quarter-finalist plays fellow Intesa Sanpaolo Next Gen ATP Finals alumnus Sebastian Baez in the first round and the highest seed in his quarter of the draw is eighth seed Hubert Hurkacz. Borna Coric, who last week won the Western & Southern Open, could challenge Alcaraz in the third round.

Medvedev, who along with Nadal, Alcaraz, Stefanos Tsitsipas and Casper Ruud has a chance to leave New York as World No. 1, opens his title defence against American Stefan Kozlov, whom he defeated 6-2, 6-2 in 2016 Wimbledon qualifying, their only previous professional meeting.

The 26-year-old could play rapidly rising American Ben Shelton in the third round and red-hot Nick Kyrgios in what would be a blockbuster fourth round. Kyrgios defeated Medvedev in three sets in Montreal earlier this month. The Australian will focus on his first match, though, as he faces a tough opening test against a player whom he often calls a “brother”, countryman Thanasi Kokkinakis.

Fourth seed Tsitsipas has never moved into the second week in New York. The Greek will try to make a good start against a qualifier, with dangerous serve-and-volleying American Maxime Cressy looming in the third round.

Ruud, who advanced to the third round at the US Open in 2020, is the fifth seed. The Norwegian star will play Briton Kyle Edmund in the first round. World No. 666 Edmund is recovering from injury, 

Dominic Thiem, who is returning to New York for the first time since winning the 2020 US Open, will begin his run against Montreal champion Pablo Carreno Busta.

Three-time US Open champion Novak Djokovic withdrew from the season’s final Grand Slam on Thursday before the draw was made due to travel restrictions.

“Sadly, I will not be able to travel to NY this time for US Open. Thank you #NoleFam for your messages of love and support,” Djokovic wrote on Twitter.. “Good luck to my fellow players! I’ll keep in good shape and positive spirit and wait for an opportunity to compete again. See you soon tennis world!”

Sadly, I will not be able to travel to NY this time for US Open. Thank you #NoleFam for your messages of love and support. ❤️ Good luck to my fellow players! I’ll keep in good shape and positive spirit and wait for an opportunity to compete again. 💪🏼 See you soon tennis world! 👋🏼

— Novak Djokovic (@DjokerNole) August 25, 2022

Djokovic owns a 23-5 record this season, including title runs at the Internazionali BNL d’Italia in Rome and Wimbledon. The Serbian is 13th in the Pepperstone ATP Live Race To Turin.

US Open Tournament Director Stacey Allaster said in a statement: “Novak is a great champion and it is very unfortunate that he will be unable to compete at the 2022 US Open, as he is unable to enter the country due to the federal government’s vaccination policy for non-U.S.citizens. We look forward to welcoming Novak back at the 2023 US Open.”

A lucky loser will replace Djokovic in the draw, which will be released later Thursday. The main draw will be played from 29 August-11 September.

The world’s best tennis players will face one another over the next fortnight with the US Open trophy at stake. On Wednesday evening, however, they banded together for a Tennis Plays For Peace exhibition in support of Ukrainian humanitarian relief.

Rafael Nadal, Iga Swiatek, Coco Gauff, John McEnroe and many more stars thrilled a packed Louis Armstrong Stadium for two hours of tennis to raise money for those suffering in Ukraine, with recently retired Ukrainian players Sergiy Stakhovsky and Olga Savchuk in attendance.

“[It has been a] very tough couple of years in terms of [the] pandemic, now with the war,” Nadal said. “Excited to be back of course, always a pleasure to play in New York and in front of probably the best crowd of the world.”

After an opening ceremony featuring Stakhovsky, Savchuk and host Patrick McEnroe, the Ukrainian national anthem was performed and Nadal took the court for a mixed doubles match alongside Swiatek against Gauff and McEnroe.

“Being on the court with John, Rafa and Iga, World No. 1, it’s really crazy here in New York,” Gauff said. “I’m happy that I’m able to do it for this cause and you guys all know me, I like to speak out when it’s right. I’m glad that I was able to be a part of this.”

^{Savchuk and Stakhovsky chat with Nadal and Swiatek during the exhibition.}
Swiatek snuck in a joke about ‘Coach Rafa’: “On the last point [he] told me that John is going to serve wide and he was wrong. He’s wrong sometimes, wow!” she said as Nadal laughed. Swiatek has previously held her own charity event in support of Ukrainian children. The World No. 1 was happy to spend her time for the cause again.

“I’m pretty happy that we are united and that we as public persons and athletes are doing so much. For sure the event that I did in Poland was a great experience for me. That was the first event that gained so much attention in tennis in Poland,” Swiatek said. “I’m pretty happy that we raised so much money for kids in Ukraine, mostly because their lives have changed and it’s right next to my country, so I was pretty emotional and pretty happy that I can use my sport that way and that we’re doing this today. It’s great.”

McEnroe, who also ironically spent time as the chair umpire later in the event, grew up 15 minutes from Flushing Meadows. The former World No. 1 thanked the crowd for their support.

“I just want to say for this event, we’re all a fraternity, the tennis players. We’re pulling for each other,” McEnroe reflected. “Obviously we all want peace and hopefully this will do something towards helping the situation over in Ukraine.”

All matches during the event were tie-breaks with the winning team being the first to 10. Americans Jessica Pegula and Ben Shelton faced Canadians Felix Auger-Aliassime and Leylah Fernandez (with John McEnroe in the chair), Italian Matteo Berrettini and Ukrainian Katarina Zavatsksa played Greeks Maria Sakkari and Stefanos Tsitsipas, Spaniard Carlos Alcaraz and American Frances Tiafoe took on Americans Taylor Fritz and Tommy Paul, and Tiafoe stayed on the court to partner Ukrainian Dayana Yastremska against American Sebastian Korda and Ukrainian Daria Snigur.

While these were exhibition matches — at one point Paul used a giant tennis racquet, drawing roars from the crowd — the stakes were raised. Before Sakkari served to Berrettini, Tsitsipas said he would donate $10,000 if the Italian missed the return. Berrettini missed it, and Tsitsipas happily reaffirmed his donation.

All proceeds from the event will benefit Global Giving’s Ukraine Crisis Relief Fund. The USTA has previously announced that it expects to raise at least $2 million for the cause during the US Open.