MELBOURNE, Australia – When the top half of the 2016 Australian Open women’s singles draw gets rolling on Monday in Melbourne, fans won’t be left wanting for star power. Four Top 6 seeds will take the court, led by six-time champion Serena Williams and 2008 champion Maria Sharapova. Here’s a rundown of key matches to see.

Monday, Day 1
First Round

[1] Serena Williams (USA #1) vs. Camila Giorgi (ITA # 36)
Head-to-head: Williams leads 2-0
Key Stat: Williams has won 8 of 14 major titles since Patrick Mouratoglou became her coach.

Four words can neatly summarize Serena Williams’ mood as she prepares her Australian Open title defense. “I don’t look back,” says Williams, who is ready, willing and able to kick off her 2016 with a continuation of a march to history that was temporarily halted in New York last season. But her first challenge, against the highest-ranked unseeded player in the draw, promises to be a tricky one.
Italy’s Camila Giorgi pushed Williams to a tie-break during Fed Cup action last season, and she’ll hope to take advantage of the 34-year-old’s lack of match play- Williams pulled out of Hopman Cup with knee inflammation but says she’s injury-free in Melbourne – to gain an early upper hand. But Williams knows a thing or two about overcoming challenges early in Slams. She holds a 60-1 lifetime record in first rounds at majors, and has never lost one in Australia.

Pick: Williams in three

[25] Samantha Stosur (AUS #27) vs. [Q] Kristyna Pliskova (CZE # 114)
Head-to-head: First meeting
Key Stat: Stosur has never been past the round of 16 at Melbourne.

One of the most beloved Aussie athletes in recent history has yet to find her mojo at the Happy Slam, but hope springs eternal as former US Open champion Sam Stosur prepares to make her 14th career appearance in Melbourne. Though she’s only made the second week twice (and not since 2010), the experienced Stosur knows that if she plays her tennis she’ll have an opportunity to rack up a win over the talented yet unheralded Pliskova. “I want to handle myself well, play well, do the things that I need to be doing, put myself in good positions hopefully to win many matches,” Stosur said. “If I can do all that and play to my ability, then I’ll be happy.” Pliskova, the identical twin of No.9 seed Karolina Pliskova, has mustered a 5-9 lifetime record at majors, and has not appeared in the main draw of the Australian Open since 2013.

Pick: Stosur in three

[4] Agnieszka Radwanska (POL #4) vs. Christina McHale (USA # 65)
Head-to-head: Radwanska leads, 3-0
Key Stat: Radwanska has dropped only seven games in three matches versus McHale.

Many pundits are predicting a big year for Poland’s Agnieszka Radwanska, and the 26-year-old has already started on the right foot by taking the Shenzhen title without the loss of a set. Radwanska, a semifinalist at Melbourne (2014) and a five-time quarterfinalist here, will face a player that has given her very little trouble in the past. The youthful, talented McHale has been troubled by the Radwanska match-up, and with red-hot Radwanska having won 22 of 26 matches dating back to last year, the challenge of coping with the unorthodox stylings of the crafty Pole promises to be even more difficult for the American.

Pick: Radwanska in two.

[5] Maria Sharapova (RUS #5) vs. Nao Hibino (JPN # 56)
Head-to-head: First meeting
Key Stat: Sharapova has played just seven tour-level matches since Wimbledon 2015.

Can Maria Sharapova shake the rust off in time to get past rapidly-rising Nao Hibino on Monday in Melbourne? The Russian has not played since the Fed Cup final last November, but she is confident that her short, sweet off-season training block and her experience will help get her through the early rounds in Melbourne. “Yes I might be more rusty,” Sharapova told reporters on Saturday, “but I’ve always been someone who treats practice as meaningful and I can take that into matches. I’m ready to go.” In Hibino, Sharapova will face one of the breakout performers of 2015. The 21-year-old won her first WTA title at Tashkent and finished a season inside the Top 100 for the first time.

Pick: Sharapova in two.

More must-see tennis: Eugenie Bouchard will look to continue her fine run of form against the always-dangerous Aleksandra Krunic in the pair’s first-ever meeting. Bouchard reached her first WTA final in well over a year over the weekend in Hobart… Italy’s Roberta Vinci begins her final Grand Slam season with a battle against Austria’s Tamira Paszek. Though Paszek is ranked more than 100 places lower than Vinci, she owns a 2-0 record versus the Italian and has never dropped a set against Vinci… Luksika Kumkhum pulled one of the biggest upsets of the 2014 Australian Open when she upset sixth-seeded Petra Kvitova in the first round. Will lightning strike twice for the Thai qualifier, or will Kvitova get her revenge… France’s Kristina Mladenovic got an exceptionally tough draw this year at Melbourne. Seeded for the first time at the Aussie Open, she drew former finalist Dominika Cibulkova, whom she has lost all five previous encounters against.