Andy Murray will be hoping to prevent Fernando Verdasco from gaining the upper hand during Wednesday’s second-round encounter at the US Open.

The 31-year-old plays the Spanish 31st seed in the second match on Arthur Ashe Stadium at about 19:00 BST.

Murray beat James Duckworth on Monday in his first Grand Slam match in 14 months after hip surgery.

British number two Cameron Norrie faces Serb Dusan Lajovic in the third match on court 10 at approximately 20:00.

Murray said: “Fernando is a great shot-maker and someone, that when he’s on his game, is really tough to beat.”

Verdasco said: “I need to treat it like any other meeting, it won’t change just because he has been injured. Hopefully, Wednesday is going to be a good day for me.”

Murray, the 2012 US Open champion, has won 13 of his 14 meetings with Verdasco but had to come from two sets down to beat him in the 2013 Wimbledon quarter-finals.

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Norrie wants bigger prizes for London home

Norrie, who beat Jordan Thompson in his opening match, has enjoyed a rapid rise up the rankings since turning professional in spring 2017 and is now up to 67 in the world.

To date, the 23-year-old has earned £522,000 in prize money, with at least an extra £42,000 from this year’s US Open.

Norrie, who is based at his former college in Texas, USA, is hoping use his prize money to buy a London flat.

He joked of the property prices: “I’ll probably have to make the semis here. Maybe [I’ll need to] win it for Putney or Wimbledon.”

Serena Williams and Nadal headline night session

As they did on Monday, defending men’s champion Rafael Nadal and six-time women’s champion Serena Williams feature in the night session on Arthur Ashe Stadium.

American Williams, seeded 17th, faces German Carina Witthoeft at 00:00 and will be followed by Nadal’s match against Canadian Vasek Pospisil.

Defending women’s champion Sloane Stephens opens proceedings on the main court at 16:00 against Ukraine’s Anhelina Kalinina, with Murray straight after.

Women’s seventh seed Elina Svitolina, two-time champion Venus Williams and men’s third seed Juan Martin del Potro are all in action on the Louis Armstrong Stadium.

If both Williams sisters win, they will meet in the third round.

Australian Open champion Caroline Wozniacki beat Australian Sam Stosur 6-3 6-2 to reach the second round of the US Open in New York.

Second seed Wozniacki, 28, broke the 2011 champion’s serve three times in the first set and twice in the second.

The Dane will play Ukrainian Lesia Tsurenko in round three.

Fifth seed and two-time Wimbledon champion Petra Kvitova beat Belgian Yanina Wickmayer 6-1 6-4 at Flushing Meadows.

The Czech, 28, broke serve twice to take the first set and won five successive games from 4-1 down in the second. She will face China’s Yafan Wang next.

Kvitova, who reached the quarter-finals in 2017, said: “I’m not really looking too much ahead. I played great tennis here last year and it was amazing for me.

“So far this year it has been great too. It is good to be in the second round of another Grand Slam and to be playing good tennis.”

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Latvian 10th seed Jelena Ostapenko, the 2017 French Open champion, beat Germany’s Andrea Petkovic 6-4 4-6 7-5 to set up a second-round meeting with American Taylor Townsend.

Japan’s Naomi Osaka, seeded 20th, defeated German Laura Siegemund 6-3 6-2 and will play Romani’s Monica Niculescu or Israel’s Julia Glushko next.

Wimbledon champion and fourth seed Angelique Kerber will face Russia’s Margarita Gasparyan on Louis Armstrong.

Top seed Simona Halep was knocked out in the first round on Monday.