NEW YORK, NY, USA – It has been an axiomatic to the point of cliché statement about Serena Williams’ prospects at any tournament, that if she is physically fit and motivated, she’s the overwhelming favorite at every tournament she enters.

But it’s true. This year there are no questions about motivation as she heads to the last Slam of the season. Once again she will be playing for history, but this year it will be history on two fronts.

Serena is aiming to break the record she currently holds with Stefanie Graf for the most major singles titles in the Open Era. She matched that record in July by winning her seventh Wimbledon title and 22nd major overall. A seventh US Open victory here would give Serena sole possession of the modern record.

“I’m cheering her on, yes,” Graf told CNN’s Open Court. “Because it’s great for the sport. Why not? She’s done so much for the sport. She’s out there working hard.”

Regardless of what happens over the next two weeks, Serena will also leave New York having tied Graf’s record for consecutive weeks at No.1 at 186 weeks. But with the top ranking under threat from No.2 Angelique Kerber, No.3 Garbiñe Muguruza, and No.4 Agnieszka Radwanska, Serena must make at least the semifinals to have a chance of remaining in the top spot on the Monday after the tournament. If she can secure the No.1 ranking after the US Open she will break Graf’s record outright and add to an era-defining resume that already spans the length of the new Arthur Ashe Stadium roof.

“I’m happy for her, I’m excited for her,” Graf said. “It’s cool that records are being broken, that’s what they’re there for. She’s been phenomenal for the sport of tennis, it has been great to watch. I hope she does break it.”

The questions concerning Serena surround the state of her right shoulder. She withdrew from the Rogers Cup earlier this month with shoulder inflammation and was clearly compromised in her third round loss to Elina Svitolina at the Olympic tennis event. For the first time since 2009, Serena heads to the US Open without a summer hard court title under her belt, having played just three singles matches since Wimbledon.

Her withdrawal from the Western & Southern Open last week was particularly worrisome. Serena was not originally entered in the event but took a late wildcard a few days before the tournament. She came to Cincinnati, cut her first practice short after less than an hour and subsequently withdrew, again citing shoulder inflammation.

Serena doesn’t lose often in New York, and a good draw that would give her time to play herself into form and confidence might be all that she needs. Since coming back from injury and illness in 2011, the World No.1 is 32-2, adding three more US Open titles to her major haul. Since returning to No.1 in 2013, Serena has never lost to a Top 10 player in New York, though the last time she faced a Top 10 player here was back in 2013, an indication of just how frequently the draw has been breaking the last two years.

To do it all Serena’s serve will need to be at the ready, and all eyes will be on that singular shot during the first week of the tournament. Notably, she will have a day’s rest between singles matches, which was not the case in Rio. If the scheduling breaks her way and she’s able to get the rest and recovery time she needs between matches, No.23 is well within striking distance.